5-HT2C Serotonin Receptor

A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.

Also Known As:

Receptor, Serotonin, 5-HT2C; 5-HT(2C) Receptor; 5-HT2C Receptor; 5-Hydroxytryptamine Type 2C Receptor; 5-Hydroxytryptamine Type 2C Receptors; Receptor, 5-Hydroxytryptamine Type 2C; 5 HT2C Receptor; 5 Hydroxytryptamine Type 2C Receptor; 5 Hydroxytryptamine Type 2C Receptors; Receptor, 5 Hydroxytryptamine Type 2C; Receptor, 5-HT2C; Receptor, Serotonin 2C; Serotonin 2C Receptor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - G-Protein-Coupled Receptors: 4701
        Serotonin Receptors: 1874
        5-HT2 Serotonin Receptors: 32
        5-HT2C Serotonin Receptor: 340
      - Neurotransmitter Receptors: 562
        Serotonin Receptors: 1874
        5-HT2 Serotonin Receptors: 32
        5-HT2C Serotonin Receptor: 340
      - Biogenic Amine Receptors: 8
        Serotonin Receptors: 1874
        5-HT2 Serotonin Receptors: 32
        5-HT2C Serotonin Receptor: 340

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Disease

Drug/Important Bio-Agent (IBA)